South Dakota Medication Aide Practice Test

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True or False: Proton pump inhibitors can safely be crushed, opened, or chewed.

True

False

Proton pump inhibitors (PPIs) are designed to be extended-release medications that are formulated to deliver the drug slowly over time. Crushing, opening, or chewing these medications can disrupt this extended-release mechanism, leading to a rapid release of the active ingredient. This could result in an increased risk of side effects or an inadequate therapeutic effect, as the medication may not work as intended.

PPIs often have protective coatings that allow them to pass through the stomach and dissolve in the more alkaline environment of the intestines. Altering their form can also expose the stomach lining to higher concentrations of the drug, potentially causing irritation.

Due to these reasons, it is crucial to follow specific guidelines and manufacturer recommendations regarding the administration of PPIs, which typically advise against altering the form of the medication unless explicitly directed by a healthcare provider.

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Only if prescribed

Only for short-term use

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