Which of the following are considered anti-thyroid drugs?

The selection of Propylthiouracil and Methimazole as anti-thyroid drugs is appropriate because both medications are specifically used to manage hyperthyroidism, a condition where the thyroid gland produces excessive amounts of thyroid hormones. These medications work by inhibiting the production of thyroid hormones, thereby helping to control the symptoms and effects of hyperthyroidism in patients.

Propylthiouracil and Methimazole act on the thyroid gland itself, making them effective in reducing thyroid hormone levels. Propylthiouracil can also inhibit the peripheral conversion of T4 to the more active T3 hormone, providing additional therapeutic benefits.

In contrast, the other groups of medications listed do not have any role in treating hyperthyroidism. For instance, Levothyroxine and Liothyronine are actually thyroid hormone replacement therapies used to treat hypothyroidism, not hyperthyroidism. Metformin and Glyburide are antidiabetic medications, primarily used to control blood sugar levels in patients with diabetes. Lastly, Ibuprofen and Acetaminophen serve primarily as analgesics and antipyretics, effective for pain relief and reducing fever, and are not related to thyroid function or treatment.